Goldman Sachs Group. has been granted a patent for a solid pharmaceutical formulation featuring a dispersible tablet containing misoprostol. This tablet, designed for sublingual or oral administration, is intended for cervical ripening and managing postpartum or post-abortion hemorrhage, with specific ingredient compositions outlined. GlobalData’s report on Goldman Sachs Group gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Goldman Sachs Group, Digital lending was a key innovation area identified from patents. Goldman Sachs Group's grant share as of June 2024 was 81%. Grant share is based on the ratio of number of grants to total number of patents.
Dispersible tablet formulation for misoprostol administration
The granted patent US12005041B2 describes a pharmaceutical tablet formulation that utilizes misoprostol, or its pharmaceutically acceptable salts, as the sole active ingredient. The tablet is designed for sublingual or oral administration and is characterized as an immediate release dosage form. The formulation includes specific weight percentages of excipients: crospovidone (5-20 wt %), a cross-linked polymer of carboxymethyl cellulose (5-20 wt %), starch (5-20 wt %), microcrystalline cellulose (30-85 wt %), and a flow agent (0.1-2 wt %). The total weight of these ingredients, along with misoprostol, must not exceed 100 wt %. The patent also specifies that the tablet should disintegrate rapidly, with a disintegration time of less than 15 seconds, and can disperse in water within a specified timeframe.
Additionally, the patent outlines various specific formulations and characteristics of the tablet, including the potential use in cervical ripening or labor induction, particularly for pregnant women. It details alternative compositions with precise weight percentages for the excipients, such as crospovidone, croscarmellose sodium, and starch. The tablet is noted for its ability to disintegrate upon contact with minimal amounts of water and to slide on a tilted surface without adhering to it. The patent further emphasizes the tablet's performance in terms of dispersion in water, ensuring that it can pass through a sieve screen after being stirred in water, indicating its suitability for immediate release and effective administration.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
