Syncona has been granted a patent for an eye therapeutic delivery apparatus. It features a flexible cannula and a needle designed to deliver agents between the choroid and sclera, targeting areas adjacent to the neurosensory retina and retinal pigment epithelium, particularly for conditions like geographic atrophy. GlobalData’s report on Syncona gives a 360-degree view of the company including its patenting strategy. Buy the report here.

According to GlobalData’s company profile on Syncona, was a key innovation area identified from patents. Syncona's grant share as of June 2024 was 30%. Grant share is based on the ratio of number of grants to total number of patents.

Apparatus for delivering therapeutic agents to the eye

Source: United States Patent and Trademark Office (USPTO). Credit: Syncona Ltd

The patent US11998482B2 describes a specialized medical apparatus designed for use in ocular procedures. The apparatus consists of a flexible cannula that extends distally from a body, featuring an atraumatic distal end intended to facilitate separation between the choroid and sclera of a patient's eye during insertion. A key component of the apparatus is a needle that is slidably housed within the cannula. This needle is equipped with a sharp distal tip and a pre-bent portion that is resiliently biased to an angled state, allowing it to transition between an angled position and a straight position depending on its location relative to the cannula. The design ensures that the needle can be safely advanced while minimizing trauma to the surrounding ocular tissues.

Further specifications of the apparatus include the cannula's non-circular cross-sectional profile, which may feature opposing flat and rounded sides, enhancing its flexibility and maneuverability. The needle's pre-bent portion is designed to maintain a predetermined angle, approximately 20 degrees, when outside the cannula, while being constrained to a straight path when inside. This innovative design aims to improve the precision and safety of ocular interventions, potentially benefiting surgical outcomes in eye care. The materials used, such as nitinol for the needle, contribute to the apparatus's functionality and durability, making it a significant advancement in the field of ophthalmic surgery.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.